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1

Thinking about health care differently: nurse practitioners in primary health care as social entrepreneurs

Kirkman, Amber, Wilkinson, Jill, Scahill, Shane

Journal:

Journal of Primary Health Care

Year:

2018

Language:

english

File:

PDF, 1.26 MB

english, 2018

2

The Synthesis and Pharmacological Evaluation of Adamantane-Derived Indoles: Cannabimimetic Drugs of Abuse

Banister, Samuel D., Wilkinson, Shane M., Longworth, Mitchell, Stuart, Jordyn, Apetz, Nadine, English, Katrina, Brooker, Lance, Goebel, Catrin, Hibbs, David E., Glass, Michelle, Connor, Mark, McGregor

Journal:

ACS Chemical Neuroscience

Year:

2013

Language:

english

File:

PDF, 1.69 MB

english, 2013

3

Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA

Banister, Samuel D., Moir, Michael, Stuart, Jordyn, Kevin, Richard C., Wood, Katie E., Longworth, Mitchell, Wilkinson, Shane M., Beinat, Corinne, Buchanan, Alexandra S., Glass, Michelle, Connor, Mark,

Journal:

ACS Chemical Neuroscience

Year:

2015

Language:

english

File:

PDF, 1.73 MB

english, 2015

4

Improved accessibility to the desoxy analogues of Δ9-tetrahydrocannabinol and cannabidiol

Wilkinson, Shane M., Price, Jason, Kassiou, Michael

Journal:

Tetrahedron Letters

Year:

2013

Language:

english

File:

PDF, 573 KB

english, 2013

5

The effect of reduced street lighting on road casualties and crime in England and Wales: controlled interrupted time series analysis

Steinbach, Rebecca, Perkins, Chloe, Tompson, Lisa, Johnson, Shane, Armstrong, Ben, Green, Judith, Grundy, Chris, Wilkinson, Paul, Edwards, Phil

Journal:

Journal of Epidemiology & Community Health

Year:

2015

Language:

english

File:

PDF, 975 KB

english, 2015

6

The terminal step in vitamin C biosynthesis in Trypanosoma cruzi is mediated by a FMN-dependent galactonolactone oxidase

Logan, Flora J., Taylor, Martin C., Wilkinson, Shane R., Kaur, Harparkash, Kelly, John M.

Journal:

Biochemical Journal

Year:

2007

Language:

english

File:

PDF, 319 KB

english, 2007

7

Synthesis and structure–activity relationships of nitrobenzyl phosphoramide mustards as nitroreductase-activated prodrugs

Longqin Hu, Xinghua Wu, Jiye Han, Lin Chen, Simon O. Vass, Patrick Browne, Belinda S. Hall, Christopher Bot, Vithurshaa Gobalakrishnapillai, Peter F. Searle, Richard J. Knox, Shane R. Wilkinson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 472 KB

english, 2011

8

Evidence that trypanothione reductase is an essential enzyme in Leishmania by targeted replacement of the tryA gene locus

Jorge Tovar, Shane Wilkinson, Jeremy C. Mottram, Alan H. Fairlamb

Journal:

Molecular Microbiology

Year:

1998

Language:

english

File:

PDF, 405 KB

english, 1998

9

Spo0A directly controls the switch from acid to solvent production in solvent-forming clostridia

Adriana Ravagnani, Katrin C. B. Jennert, Elisabeth Steiner, Raik Grünberg, James R. Jefferies, Shane R. Wilkinson, Danielle I. Young, Edward C. Tidswell, David P. Brown, Philip Youngman, J. Gareth Mor

Journal:

Molecular Microbiology

Year:

2000

Language:

english

File:

PDF, 703 KB

english, 2000

10

Structure and non-essential function of glycerol kinase in Plasmodium falciparum blood stages

Claudia Schnick, Spencer D. Polley, Quinton L. Fivelman, Lisa C. Ranford-Cartwright, Shane R. Wilkinson, James A. Brannigan, Anthony J. Wilkinson, David A. Baker

Journal:

Molecular Microbiology

Year:

2009

Language:

english

File:

PDF, 1.00 MB

english, 2009

11

Molecular genetics and the initiation of solventogenesis in Clostridium beijerinckii (formerly Clostridium acetobutylicum) NCIMB 8052

Shane R. Wilkinson, Danielle I. Young, J. Gareth Morris, Michael Young

Journal:

FEMS Microbiology Reviews

Year:

1995

Language:

english

File:

PDF, 973 KB

english, 1995

12

Characterization of spo0A homologues in diverse Bacillus and Clostridium species identifies a probable DNA-binding domain

David P. Brown, Lilia Ganova-Raeva, Brian D. Green, Shane R. Wilkinson, Michael Young, Philip Youngman

Journal:

Molecular Microbiology

Year:

1994

Language:

english

File:

PDF, 10.64 MB

english, 1994

13

Cloning of an Fe-superoxide dismutase gene homologue from Trypanosoma cruzi

Nigel J. Temperton, Shane R. Wilkinson, John M. Kelly

Journal:

Molecular and Biochemical Parasitology

Year:

1996

Language:

english

File:

PDF, 408 KB

english, 1996

14

Molecular genetics and the initiation of solventogenesis in Clostridium beijerinckii (formerly Clostridium acetobutylicum) NCIMB 8052

Shane R. Wilkinson, Danielle I. Young, J. Gareth Morris, Michael Young

Journal:

FEMS Microbiology Reviews

Year:

1995

Language:

english

File:

PDF, 987 KB

english, 1995

15

Synthesis and antikinetoplastid activity of a series of N,N′-substituted diamines

Andrea P. Caminos, Esteban A. Panozzo-Zenere, Shane R. Wilkinson, Babu L. Tekwani, Guillermo R. Labadie

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 313 KB

english, 2012

16

Functional characterisation of the iron superoxide dismutase gene repertoire in Trypanosoma brucei

Shane R. Wilkinson, S. Radhika Prathalingam, Martin C. Taylor, Aiyaz Ahmed, David Horn, John M. Kelly

Journal:

Free Radical Biology and Medicine

Year:

2006

Language:

english

File:

PDF, 572 KB

english, 2006

17

Insights into the redox biology of Trypanosoma cruzi: Trypanothione metabolism and oxidant detoxification

Florencia Irigoín, Lucía Cibils, Marcelo A. Comini, Shane R. Wilkinson, Leopold Flohé, Rafael Radi

Journal:

Free Radical Biology and Medicine

Year:

2008

Language:

english

File:

PDF, 558 KB

english, 2008

18

Erratum to “The amino terminal domain of a novel WD repeat protein from Trypanosoma cruzi contains a non-canonical mitochondrial targeting signal” [Int. J. Parasitol. 34(1) (2004) 63–71]

Elizabeth V Bromley, Martin C Taylor, Shane R Wilkinson, John M Kelly

Journal:

International Journal for Parasitology

Year:

2004

Language:

english

File:

PDF, 61 KB

english, 2004

19

The amino terminal domain of a novel WD repeat protein from Trypanosoma cruzi contains a non-canonical mitochondrial targeting signal

Elizabeth V. Bromley, Martin C. Taylor, Shane R. Wilkinson, John M. Kelly

Journal:

International Journal for Parasitology

Year:

2004

Language:

english

File:

PDF, 330 KB

english, 2004

20

Ontogenetic variation in site fidelity and homing behaviour of a temperate reef fish

Jeffrey S. Shima, Daniel McNaughtan, Shane W. Geange, Shaun Wilkinson

Journal:

Journal of Experimental Marine Biology and Ecology

Year:

2012

Language:

english

File:

PDF, 360 KB

english, 2012

21

A practical, multigram synthesis of the 2-(2-(4-alkoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide (DPA) class of high affinity translocator protein (TSPO) ligands

Samuel D. Banister, Shane M. Wilkinson, Raphy Hanani, Aaron J. Reynolds, David E. Hibbs, Michael Kassiou

Journal:

Tetrahedron Letters

Year:

2012

Language:

english

File:

PDF, 261 KB

english, 2012

22

Overexpression of superoxide dismutase in Trypanosoma cruzi results in increased sensitivity to the trypanocidal agents gentian violet and benznidazole

Nigel J. Temperton, Shane R. Wilkinson, David J. Meyer, John M. Kelly

Journal:

Molecular and Biochemical Parasitology

Year:

1998

Language:

english

File:

PDF, 330 KB

english, 1998

23

Trypanocidal drugs: mechanisms, resistance and new targets

Wilkinson, Shane R., Kelly, John M.

Journal:

Expert Reviews in Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 710 KB

english, 2009

24

Novel 3-Nitro-1 H -1,2,4-triazole-Based Amides and Sulfonamides as Potential Antitrypanosomal Agents

Papadopoulou, Maria V., Bloomer, William D., Rosenzweig, Howard S., Chatelain, Eric, Kaiser, Marcel, Wilkinson, Shane R., McKenzie, Caroline, Ioset, Jean-Robert

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 619 KB

english, 2012

25

Novel 3-Nitro-1 H -1,2,4-triazole-Based Aliphatic and Aromatic Amines as Anti-Chagasic Agents

Papadopoulou, Maria V., Trunz, Bernadette Bourdin, Bloomer, William D., McKenzie, Caroline, Wilkinson, Shane R., Prasittichai, Chaiya, Brun, Reto, Kaiser, Marcel, Torreele, Els

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.17 MB

english, 2011

26

Evaluating the developmental toxicity of trypanocidal nitroaromatic compounds on zebrafish

Buchanan-Kilbey, Grace, Djumpah, Joshua, Papadopoulou, Maria V., Bloomer, William, Hu, Lonqin, Wilkinson, Shane R., Ashworth, Rachel

Journal:

Year:

2013

Language:

english

File:

PDF, 1.15 MB

english, 2013

27

Synthesis and anti-parasitic activity of a novel quinolinone–chalcone series

Roussaki, Marina, Hall, Belinda, Lima, Sofia Costa, da Silva, Anabela Cordeiro, Wilkinson, Shane, Detsi, Anastasia

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 632 KB

english, 2013

28

The First CNS-Active Carborane: A Novel P2X 7 Receptor Antagonist with Antidepressant Activity

Wilkinson, Shane M., Gunosewoyo, Hendra, Barron, Melissa L., Boucher, Aurelie, McDonnell, Michelle, Turner, Peter, Morrison, Daniel E., Bennett, Maxwell R., McGregor, Iain S., Rendina, Louis M., Kassi

Journal:

ACS Chemical Neuroscience

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

29

Corrigendum to “Synthesis and antikinetoplastid activity of a series of N,N′-substituted diamines” [Bioorg. Med. Chem. Lett. 22 (2012) 1712–1715]

Caminos, Andrea P., Panozzo-Zenere, Esteban A., Wilkinson, Shane R., Tekwani, Babu L., Labadie, Guillermo R.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 120 KB

english, 2013

30

Design, synthesis, and evaluation of potential prodrugs of DFMO for reductive activation

Yang, Yanhui, Voak, Andrew, Wilkinson, Shane R., Hu, Longqin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 978 KB

english, 2012

31

Bioisosteric Fluorine in the Clandestine Design of Synthetic Cannabinoids

Wilkinson, Shane M., Banister, Samuel D., Kassiou, Michael

Journal:

Australian Journal of Chemistry

Year:

2015

Language:

english

File:

PDF, 440 KB

english, 2015

32

Experimental and Kinetic Studies of the Escherichia coli Glucuronylsynthase: An Engineered Enzyme for the Synthesis of Glucuronide Conjugates

Wilkinson, Shane M., Watson, Morgan A., Willis, Anthony C., McLeod, Malcolm D.

Journal:

Journal of Organic Chemistry

Year:

2011

Language:

english

File:

PDF, 1.98 MB

english, 2011

33

Novel nitro(triazole/imidazole)-based heteroarylamides/sulfonamides as potential antitrypanosomal agents

Papadopoulou, Maria V., Bloomer, William D., Rosenzweig, Howard S., Wilkinson, Shane R., Kaiser, Marcel

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.78 MB

english, 2014

34

E scherichia coli Glucuronylsynthase: An Engineered Enzyme for the Synthesis of β-Glucuronides

Wilkinson, Shane M., Liew, Chu W., Mackay, Joel P., Salleh, Hamzah M., Withers, Stephen G., McLeod, Malcolm D.

Journal:

Organic Letters

Year:

2008

Language:

english

File:

PDF, 76 KB

english, 2008

35

Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase overexpression

Piacenza, Lucía, Irigoín, Florencia, Alvarez, María Noel, Peluffo, Gonzalo, Taylor, Martin C., Kelly, John M., Wilkinson, Shane R., Radi, Rafael

Journal:

Biochemical Journal

Year:

2007

Language:

english

File:

PDF, 698 KB

english, 2007

36

Structural insights into the catalytic mechanism of Trypanosoma cruzi GPXI (glutathione peroxidase-like enzyme I)

Patel, Shreenal, Hussain, Syeed, Harris, Richard, Sardiwal, Sunita, Kelly, John M., Wilkinson, Shane R., Driscoll, Paul C., Djordjevic, Snezana

Journal:

Biochemical Journal

Year:

2010

Language:

english

File:

PDF, 946 KB

english, 2010

37

Winter photosynthesis of red spruce from three Vermont seed sources

Schaberg, P. G., Wilkinson, R. C., Shane, J. B., Donnelly, J. R., Cali, P. F.

Journal:

Tree Physiology

Year:

1995

Language:

english

File:

PDF, 67 KB

english, 1995

38

Novel 3-Nitrotriazole-Based Amides and Carbinols as Bifunctional Antichagasic Agents

Papadopoulou, Maria V., Bloomer, William D., Lepesheva, Galina I., Rosenzweig, Howard S., Kaiser, Marcel, Aguilera-Venegas, Benjamín, Wilkinson, Shane R., Chatelain, Eric, Ioset, Jean-Robert

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.38 MB

english, 2015

39

Novel 3-nitro-1 H -1,2,4-triazole-based compounds as potential anti-Chagasic drugs: in vivo studies

Papadopoulou, Maria V, Bloomer, William D, Rosenzweig, Howard S, Ashworth, Rachel, Wilkinson, Shane R, Kaiser, Marcel, Andriani, Grasiella, Rodriguez, Ana

Journal:

Future Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.91 MB

english, 2013

40

Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite

Piacenza, Lucía, Peluffo, Gonzalo, Alvarez, María Noel, Kelly, John M., Wilkinson, Shane R., Radi, Rafael

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 492 KB

english, 2008

41

Effects of Bioisosteric Fluorine in Synthetic Cannabinoid Designer Drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, APICA, and STS-135

Banister, Samuel D., Stuart, Jordyn, Kevin, Richard C., Edington, Amelia, Longworth, Mitchell, Wilkinson, Shane M., Beinat, Corinne, Buchanan, Alexandra S., Hibbs, David E., Glass, Michelle, Connor, M

Journal:

ACS Chemical Neuroscience

Year:

2015

Language:

english

File:

PDF, 2.32 MB

english, 2015

42

Megazol and its bioisostere 4H-1,2,4-triazole: comparing the trypanocidal, cytotoxic and genotoxic activities and their in vitro and in silico interactions with the Trypanosoma brucei nitroreductase enzyme

Carvalho, Alcione Silva de, Salomão, Kelly, Castro, Solange Lisboa de, Conde, Taline Ramos, Zamith, Helena Pereira da Silva, Caffarena, Ernesto Raúl, Hall, Belinda Suzette, Wilkinson, Shane Robert, Bo

Journal:

Memórias do Instituto Oswaldo Cruz

Year:

2014

Language:

english

File:

PDF, 804 KB

english, 2014

43

Structure–activity relationships of synthetic cannabinoid designer drug RCS-4 and its regioisomers and C4 homologues

Banister, Samuel D., Stuart, Jordyn, Conroy, Trent, Longworth, Mitchell, Manohar, Madhura, Beinat, Corinne, Wilkinson, Shane M., Kevin, Richard C., Hibbs, David E., Glass, Michelle, Connor, Mark, McGr

Journal:

Forensic Toxicology

Year:

2015

Language:

english

File:

PDF, 909 KB

english, 2015

44

The Trypanosoma cruzi Vitamin C Dependent Peroxidase Confers Protection against Oxidative Stress but Is Not a Determinant of Virulence

Taylor, Martin C., Lewis, Michael D., Francisco, Amanda Fortes, Wilkinson, Shane R., Kelly, John M., Dumonteil, Eric

Journal:

PLoS Neglected Tropical Diseases

Year:

2015

Language:

english

File:

PDF, 9.11 MB

english, 2015

45

Ether analogues of DPA-714 with subnanomolar affinity for the translocator protein (TSPO)

Banister, Samuel D., Beinat, Corinne, Wilkinson, Shane M., Shen, Bin, Bartoli, Cecilia, Selleri, Silvia, Da Pozzo, Eleonora, Martini, Claudia, Chin, Frederick T., Kassiou, Michael

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1001 KB

english, 2015

46

Unravelling the role of SNM1 in the DNA repair system of T rypanosoma brucei

Sullivan, James A., Tong, Jie Lun, Wong, Martin, Kumar, Ambika, Sarkar, Hajrah, Ali, Sarah, Hussein, Ikran, Zaman, Iqra, Meredith, Emma Louise, Helsby, Nuala A., Hu, Longqin, Wilkinson, Shane R.

Journal:

Molecular Microbiology

Year:

2015

Language:

english

File:

PDF, 1.88 MB

english, 2015

47

Discovery of potent nitrotriazole-based antitrypanosomal agents: In vitro and in vivo evaluation

Papadopoulou, Maria V., Bloomer, William D., Rosenzweig, Howard S., O’Shea, Ivan P., Wilkinson, Shane R., Kaiser, Marcel, Chatelain, Eric, Ioset, Jean-Robert

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.33 MB

english, 2015

48

Development and use of active clinical decision support for preemptive pharmacogenomics

Bell, Gillian C, Crews, Kristine R, Wilkinson, Mark R, Haidar, Cyrine E, Hicks, J Kevin, Baker, Donald K, Kornegay, Nancy M, Yang, Wenjian, Cross, Shane J, Howard, Scott C, Freimuth, Robert R, Evans,

Journal:

Journal of the American Medical Informatics Association

Year:

2014

Language:

english

File:

PDF, 296 KB

english, 2014

49

Trypanocidal Activity of Nitroaromatic Prodrugs: Current Treatments and Future Perspectives

R. Wilkinson, Shane, Bot, Christopher, M. Kelly, John, S. Hall, Belinda

Journal:

Current Topics in Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 224 KB

english, 2011

50

Evaluating 5-nitrothiazoles as trypanocidal agents

O'Shea, Ivan P., Shahed, Mohammed, Aguilera-Venegas, Benjamín, Wilkinson, Shane R.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 717 KB

english, 2015

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